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HMGB1 (mono methyl K42) antibody
High mobility group protein B1
High mobility group protein 1, HMG-1
Gene name: HMGB1, HMG1
RP11-550P23.1, HMG3, SBP-1
High mobility group protein 1, HMG-1
Gene name: HMGB1, HMG1
RP11-550P23.1, HMG3, SBP-1
As low as
€278.30
In stock
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00013199
HMGB1 is a DAMP involved in innate immune response. It is secreted by activated dendritic cells, macrophages and necrotic cells.
| ID Covalab | pab0219 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide derived from N terminal region of HMGB1, containing mono-methyl at K42 |
| Activity cross reaction | Reacts with HMGB1 methylated on Lysine 42 from human neutrophils. Not tested in other species. May cross react with a wide range of species due to sequence homology. |
| Species | Hu |
| Labelling | None |
| Form | Antiserum |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | HMGB1 mono-methyl K42 |
| Uniprot ID | P09429 |
| Gene ID | 3146 |
| Applications | ELISA, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC 1:100 - 1:1000 WB 1:200 |
| Publication | ichiaki Ito et al. Post-translational Methylation of High Mobility Group Box 1 (HMGB1) Causes Its ytoplasmic Localization in Neutrophils.June 1, 2007 The Journal of Biological Chemistry, 282, 16336-16344. |
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