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Protein-arginine deiminase type-3 (PADI3) antibody
Protein-arginine deiminase type-3
Protein-arginine deiminase type III
Gene nmae : PADI3, PDI3
PAD3
Protein-arginine deiminase type III
Gene nmae : PADI3, PDI3
PAD3
As low as
€294.00
In stock
Ref
00013414
Catalyzes the deimination of arginine residues of proteins. Involved in protein citrullination.
| ID Covalab | pab0198-P |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | A 15 residue synthetic peptide derived from N-terminal domain of human PADI3 protein |
| Activity cross reaction | Reacts with 75 kDa PADI3 protein from mouse, human and rat. No cross reaction with the other isoforms. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Protein-arginine deiminase type-3 |
| Uniprot ID | Q9ULW8 |
| Gene ID | 51702 |
| Applications | ELISA, ICC, IF, IHC, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : ELISA (1:5000 - 1:20000) IHC/ ICC/ IF (1:50 - 1:500) IP (1:20 - 1:100) WB (1:200 - 1:2000) |
| Publication | *U KP, Subramanian V, et al. Modulation of calcium-induced cell death in human neural stem cells by the novel peptidylarginine deiminase-AIF pathway. Biochim Biophys Acta. 2014 Jun:1843(6):1162-71. (ICC, WB, IP, Hu) *Mechin M.C. et al.The peptidylarginine deiminase expressed in human epidermis differ in their substrate specificities and subcellular locations. Cell Mol Life Sci. 2005;62:1984-95. (Hu) *Kanno T. et al. Human peptidylarginine deiminase type III : molecular cloning and nucleotide sequence of the cDNA, properties of the recombinant enzyme, and immunohistochemical localization in human skin. J Invest Dermatol.2000;115:813-23.(WB, IF, Hu) |
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