We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Leukemia inhibitory factor receptor (LIFR) antibody (12D3)
Leukemia inhibitory factor receptor (LIF receptor, LIF-R)
CD118
Gene name: LIFR
CD118
Gene name: LIFR
As low as
€407.80
In stock
Ref
00122066
CD118 (LIFR alpha) is a type I transmembrane glycoprotein of the cytokine receptor family, which associates noncovalently with CD130 to form the functional high affinity LIF receptor, which also acts as an oncostatin M receptor. CD118 alone binds LIF with low affinity. A secreted form of CD118 results from alternative splicing, and may have inhibitory effect, as it also binds LIF, although with low affinity. CD118 is not expressed on lymphocytes, but it is widely expressed outside the immune system. Soluble CD118 level rises during pregnancy, in parallel with a drop in circulating LIF levels.
ID Covalab | mab21337 |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | 12D3 |
Isotype | IgG1 kappa |
Raised in | Mouse |
Immunogen | The mouse monoclonal antibody 12D3 recognizes an extracellular epitope of CD118, a transmembrane glycoprotein, which associates with CD130 to form the functional high affinity LIF receptor. |
Species | Hu |
Labelling | None |
Form | Purified (protein A) |
Preservative | NaN3 15 mM |
Storage instructions | Store at 2-8°C. Do not freeze. |
Target | LIFR |
Uniprot ID | P42702 |
Gene ID | 3977 |
Applications | ELISA, FC, WB |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : FC (2-5 µg/ml) |
Write Your Own Review