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Maf protein antibody
Proto-oncogene c-Maf
V-maf musculoaponeurotic fibrosarcoma oncogene homolog
Gene name : MAF
V-maf musculoaponeurotic fibrosarcoma oncogene homolog
Gene name : MAF
As low as
€278.30
In stock
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00013050
Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.
| ID Covalab | pab0007 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Maf-GST fusion protein |
| Activity cross reaction | Reacts with human 47 kDa Maf protein derived from a transfected CEFcell line. |
| Species | Hu |
| Labelling | None |
| Form | Antiserum |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Transcription factor Maf |
| Uniprot ID | O75444 |
| Gene ID | NP_001026974.1 |
| Applications | ELISA, EM, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : -IHC : 1/50 to 1/500 - WB : 1/200 to 1/5 000 Useful for electrophoretic mobility shift assay (EMSA) |
| Publication | - Vial E. et al. Transcriptional control of SPArc by v-jun and other members of the AP1 family of ranscription factors. Oncogene, 2000, 19,5020-5029. |
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