Podoplanin antibody

Aggrus
Glycoprotein 36 (Gp36)
PA2.26 antigen
T1-alpha (T1A)
Gene name : PDPN, GP36, PSEC0003, PSEC0025
As low as €278.30
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00013211
May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels.
More Information
ID Covalab pab0218
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide derived from internal region of human Podoplanin
Activity cross reaction Reacts with human podoplanin.
Species Hu
Labelling None
Form Antiserum
Preservative None
Storage instructions Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target Podoplanin
Uniprot ID Q86YL7
Applications ELISA, FC, IHC, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
- FC : 1/100 to 1/500
- IHC : 1/50 to 1/500
- WB : 1/200 to 1/1 000
Publication - Nisato RE, Harrison JA, Buser R, Orci L, Rinsch C, Montesano R, Dupraz P, Pepper MS. Generation and characterization of telomerase-transfected human lymphatic endothelial cells with an extended life span. Am J Pathol. 2004 Jul;165(1):11-24.
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