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Glu-alpha-Tubulin (Detyrosinated alpha-Tubulin) antibody
Detyrosinated alpha-Tubulin
Tubulin alpha-1A chain
Alpha-tubulin 3
Tubulin B-alpha-1
Tubulin alpha-3 chain
Gene name: TUBA1A, TUBA3
Tubulin alpha-1A chain
Alpha-tubulin 3
Tubulin B-alpha-1
Tubulin alpha-3 chain
Gene name: TUBA1A, TUBA3
As low as
€294.00
In stock
Ref
00013594
Human alpha-Tubulin can be detyrosinated by the tubulin tyrosine carboxypeptidase (TTCP)
| ID Covalab | pab0201-P |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | A 10 residues synthetic peptide of Cter domain of human tubulin |
| Activity cross reaction | Reacts with human, mouse and rat Glu-alpha-Tubulin (Detyrosinated alpha-tubulin). Does not cross react with alpha-tubulin. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Glu-alpha-Tubulin |
| Uniprot ID | Q71U36 |
| Gene ID | 7846 |
| Applications | ELISA, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: IHC (1:50 - 1:200) WB (1:500 - 1:2000) |
| Publication | * Peris L et al. Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends. J Cell Biol. 2006;174 :839-49. * Mialhe A. et al. Tubulin detyrosination is a frequent occurrence in breast cancers of poor prognosis. CancerRes. 2001 Jul 61: 5024-7. |
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