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Inward rectifier potassium channel 2 (KCNJ2) antibody
Cardiac inward rectifier potassium channel
Inward rectifier K(+) channel Kir2.1 (IRK-1), (hIRK1)
Potassium channel, inwardly rectifying subfamily J member 2
Gene name : KCNJ2, IRK1
Inward rectifier K(+) channel Kir2.1 (IRK-1), (hIRK1)
Potassium channel, inwardly rectifying subfamily J member 2
Gene name : KCNJ2, IRK1
As low as
€278.30
In stock
Ref
00013913
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.
| ID Covalab | pab0293 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide derived from Nter domain of KCNJ2 protein |
| Activity cross reaction | Reacts with human KCNJ2 protein. Cross reacts with protein from mouse, rat and several other species |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Antiserum |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Inward rectifier potassium channel 2 (KCNJ2) |
| Uniprot ID | P63252 |
| Applications | ELISA, ICC, IF, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC (1:50 - 1:200) WB (1:200 - 1:2000) |
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