We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
ATG4B antibody
Cysteine protease ATG4B, AUT-like 1 cysteine endopeptidase, Autophagin-1, Autophagy-related cysteine endopeptidase 1, Autophagy-related protein 4 homolog B, hAPG4B
Gene name: ATG4B, APG4B, AUTL1, MGC1353, KIAA0943
Gene name: ATG4B, APG4B, AUTL1, MGC1353, KIAA0943
As low as
€542.30
In stock
Ref
00024152
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy.
| ID Covalab | pab74475 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Isotype | IgG |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide from human ATG4B. |
| Activity cross reaction | Reacts with human ATG4B. Cross reacts with chicken, xenopus, mouse, pufferfish, rat and zebrafish protein. |
| Species | Chick, Hu, Ma, Xe, Zfi |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | NaN3 0.05% |
| Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Target | ATG4B |
| Uniprot ID | Q9Y4P1 |
| Gene ID | 23192 |
| Applications | IHC - P, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC-P (10 µg/ml), WB (1 - 3 µg/ml) |
Write Your Own Review