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SIRT1 (7B7) antibody
NAD-dependent protein deacetylase sirtuin-1, hSIRT1
Regulatory protein SIR2 homolog 1
SIR2-like protein 1, hSIR2
SirtT1 75 kDa fragment, 75SirT1
Gene name: SIRT1, SIR2L1
Regulatory protein SIR2 homolog 1
SIR2-like protein 1, hSIR2
SirtT1 75 kDa fragment, 75SirT1
Gene name: SIRT1, SIR2L1
As low as
€548.90
In stock
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00027063
NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression.
| ID Covalab | mab70724 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 7B7 |
| Isotype | IgG1 / Kappa |
| Raised in | Mouse |
| Immunogen | Human SIRT1 (AAH12499, 456 a.a. ~ 555 a.a) partial recombinant protein with GST tag. |
| Activity cross reaction | Reacts with human SIRT1. |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | +4°C or -20°C, Avoid repeated freezing and thawing. |
| Target | SIRT1 |
| Uniprot ID | Q96EB6 |
| Gene ID | 23411 |
| Applications | ELISA, IF, IHC - P, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : ELISA, IF (10 µg/ml), IHC - P (5 µg/ml), WB |
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