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NEI3 antibody
Endonuclease 8-like 3
DNA glycosylase FPG2
DNA glycosylase/AP lyase Neil3
Endonuclease VIII-like 3
Nei-like protein 3
Gene name: NEIL3
DNA glycosylase FPG2
DNA glycosylase/AP lyase Neil3
Endonuclease VIII-like 3
Nei-like protein 3
Gene name: NEIL3
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00035961
Prokaryotes and lower eukaryotes possess redundant activities that remove the plethora of oxidative DNA base damages produced during normal oxidative metabolism and which have been associated with cancer and aging. Thus far, only one oxidized pyrimidine-specific DNA glycosylase has been identified in humans, hNthl. HNEI3 is one of three new putative human DNA glycosylases.
| ID Covalab | pab50895 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Residues 164-177 (LRAESEVKKQKGRMLG) of the human NEI3 protein. 85% sequence identity to mouse and rat |
| Activity cross reaction | Reacts with human NEI3 protein. Predicted to cross react with mouse and rat. |
| Species | Hu |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | NEI3 |
| Uniprot ID | Q8TAT5 |
| Applications | WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: WB (1:500) |
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