We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Park7 / DJ-1 antibody
Protein DJ-1
Oncogene DJ1
Parkinson disease protein 7
Gene name: PARK7
Oncogene DJ1
Parkinson disease protein 7
Gene name: PARK7
Out of stock
Ref
00036088
Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.
| ID Covalab | pab50920 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | A synthetic peptide mapping to the human PARK7 (DJ-1) protein, residues 167-189. AIVEALNGKEVAAQVKAPLVLKD |
| Activity cross reaction | Reacts with human, rat and mouse (brain) PARK7. Predicted to react with monkey based on 100% sequence homology. Immunogen has 86% homology to chicken and pig. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Park7 / DJ-1 |
| Uniprot ID | Q99497 |
| Gene ID | 11315 |
| Applications | ICC, IF, IHC, IHC - P, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: ICC/ IF 1:100 - 1:500, IHC 1:1000, IHC-P 1:1000, WB 1:500-1:1000 |
Write Your Own Review