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SEMA4D antibody
Semaphorin-4D
A8
BB18
GR3
CD_antigen: CD100
Gene name: SEMA4D, C9orf164, CD100, SEMAJ
A8
BB18
GR3
CD_antigen: CD100
Gene name: SEMA4D, C9orf164, CD100, SEMAJ
As low as
€480.40
In stock
Ref
00036342
Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.
| ID Covalab | pab51039 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Isotype | IgG |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide corresponding to residues 147-158 [GKNEDGKGRCPF] of the human CD100 protein. |
| Activity cross reaction | Reacts with human CD100 protein. |
| Species | Hu |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | SEMA4D |
| Uniprot ID | Q92854 |
| Applications | WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: WB (1:100 - 1:2000) |
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