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P2Y2 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells.P2Y2is also a morphogen receptor that potentiates neurotrophin signaling in neuronal development and regeneration.
| ID Covalab | pab51082 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide comprising residues 351-366 [DVLGSSEDSRRTESTP] of the human P2Y2 protein. |
| Activity cross reaction | REacts wtih P2Y2 protein from human, mouse and rat. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | P2Y2 |
| Applications | IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: - IHC : 1/100 to 1/200 - WB : 1/500 to 1/1000 |
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