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The transcriptional factor Nanog functions in maintaining pluripotency in cooperation with other key genes such as Oct4.Oct4 and Sox2 bind to the Nanog promoter in mouse and human embryonic stem cell.Nanog levels allow stem cells to balance the creation of lineage-committed and undifferentiated cells.
ID Covalab | pab51097 |
---|---|
Product type | Primary antibodies |
Clonality | Polyclonal antibody |
Isotype | IgG |
Raised in | Rabbit |
Immunogen | Synthetic peptide comprising residues 281-296 [TRYFSTPQTMDLFLNY] of the human Nanog protein. |
Activity cross reaction | Reacts with human Nanog. Reactivity in other species unknown. |
Species | Hu |
Labelling | None |
Form | Antigen affinity purified |
Preservative | NaN3 0.02% |
Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
Target | Nanog |
Applications | WB |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : - WB : 1/1000 to 1/2000 |
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