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BRCA1 (1D12) antibody
Breast cancer type 1 susceptibility protein
RING finger protein 53
Gene name: BRCA1, RNF53
BRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP
RING finger protein 53
Gene name: BRCA1, RNF53
BRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP
As low as
€646.00
In stock
Ref
00096563
BRCA1 (1D12) antibody
| ID Covalab | mab60050 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 1D12 |
| Isotype | IgG1 / Kappa |
| Raised in | Mouse |
| Immunogen | GST fusion protein expressed in E. coli corresponding to aa 341-748 of full-length BRCA1. |
| Activity cross reaction | Reacts with human BRCA1. |
| Species | Hu |
| Labelling | None |
| Form | Purified |
| Preservative | None |
| Storage instructions | Stable for at least one year at -70°C. Avoid multiple freeze-thaw cycles. |
| Target | BRCA1 |
| Uniprot ID | P38398 |
| Gene ID | 672 |
| Applications | IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: IP (1 - 10 µg/ml) WB (1 - 10 µg/ml) |
| Publication | Chen Y et al. Aberrant subcellular localization of BRCA1 in breast cancer. Science. 1995 Nov 3,270(5237):789-91. Chen CF et al. The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor. J Biol Chem. 1996 Dec 20,271(51):32863-8. Chen Y et al. BRCA1 is a 220-kDa nuclear phosphoprotein that is expressed and phosphorylated in a cell cycle-dependent manner. Cancer Res. 1996 Jul 15,56(14):3168-72. |
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