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EAAC1 (S180-41) antibody
Excitatory amino acid transporter 3
Excitatory amino-acid carrier , EAAC1
Neuronal and epithelial glutamate transporter
Sodium-dependent glutamate/aspartate transporter 3
Solute carrier family 1 member 1
DCBXA
EAAT3
SCZD18
Gene name : SLC1A1
Excitatory amino-acid carrier , EAAC1
Neuronal and epithelial glutamate transporter
Sodium-dependent glutamate/aspartate transporter 3
Solute carrier family 1 member 1
DCBXA
EAAT3
SCZD18
Gene name : SLC1A1
As low as
€609.00
In stock
Ref
00096648
Excitatory amino-acid carrier 1 (EAAC1) is a high-affinity Na+ -dependent Lglutamate/D,L-aspartate cell membrane transport protein. It is expressed in brain as well as in several non-nervous system tissues. In brain, EAAC1 is the primary neuronal glutamate transporter. It has a polarized distribution in cells and functions mainly perisynaptically to transport glutamate from the extracellular environment. In the kidney it is involved in renal acidic amino acid reabsorption and amino acid metabolism. EAAC1- associated protein GTRAP3-18 may be important in regulating the metabolic function of EAAC1.
| ID Covalab | mab60135 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | S180-41 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Fusion protein corresponding to aa 1-524 (full-length) of human EAAC1 (accession no. NP_004161.4). |
| Activity cross reaction | Reacts with human EAAC1. |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | 0,09% NaN3 |
| Storage instructions | This antibody is stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | EAAC1 |
| Uniprot ID | P43005 |
| Gene ID | 6505 |
| Applications | IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : WB (1 - 5 µg/ml) |
| Positive control | Rat brain membranes |
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