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EndoPDI (2E7/7) antibody
Thioredoxin domain containing 5 (endoplasmic reticulum)
Endoplasmic reticulum resident protein 46, ER protein 46, ERp46
Thioredoxin-like protein p46
HCC2, HCC-2
STRF8
PDIA15
UNQ364
Gene name :TXNDC5
Endoplasmic reticulum resident protein 46, ER protein 46, ERp46
Thioredoxin-like protein p46
HCC2, HCC-2
STRF8
PDIA15
UNQ364
Gene name :TXNDC5
As low as
€609.00
In stock
Ref
00096649
Endothelial protein disulfide isomerase (EndoPDI) is a thiredoxin member of the protein disulfide isomerase family of chaperones. This enzyme is localized in the endoplasmic reticulum in primary endothelial cells but colocalizes with nucleoli in the nuclei of breast, colon, and kidney cancer cells. EndoPDI mRNA and protein expression is iduced by hypoxia and exhibits a protective effect on endothelial cells during hypoxia.
| ID Covalab | mab60136 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 2E7/7 |
| Isotype | IgG2a |
| Raised in | Mouse |
| Immunogen | Synthetic peptide corresponding to aa 52-63 (ADGEDGQDPHSK) of human EndoPDI (accession no. NP_001139021). |
| Activity cross reaction | Reacts with human EndoPDI. |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | 0,09% NaN3 |
| Storage instructions | This antibody is stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | EndoPDI |
| Uniprot ID | Q8NBS9 |
| Gene ID | 81567 |
| Applications | ELISA, ICC, IF, IHC, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : ICC (1:10 - 1:500) IF (1:10 - 1:500) IHC (1:10 - 1:500) IP (1:10 - 1:500) WB (1 µg/ml) |
| Positive control | Heat-shocked HeLa cell lysate. |
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