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ESE-1 antibody
ETS-related transcription factor Elf-3
E74-like factor 3
Epithelial-restricted with serine box
Epithelium-restricted Ets protein ESX
Epithelium-specific Ets transcription factor 1, ESE-1
Gene name: ELF3, ERT, ESX, JEN
E74-like factor 3
Epithelial-restricted with serine box
Epithelium-restricted Ets protein ESX
Epithelium-specific Ets transcription factor 1, ESE-1
Gene name: ELF3, ERT, ESX, JEN
As low as
€520.00
In stock
Ref
00097838
Epithelium-specific gene regulation plays a critical role during embryogenesis, and the epithelial cell lineage is the first differentiated cell type to appear after fertilization. Until recently, very few epithelial cell-restricted transcription factors had been described. Members of the ets transcription factor/oncogene family have been implicated in human carcinogenesis following the discovery of several distinct chromosomal translocations involving members of the ets family in different types of cancer. ets factors play key roles in transcriptional control of stringently regulated genes, such as genes involved in tissue development, differentiation, angiogenesis, cell cycle control and cell proliferation. ESE-1 is the first member of the ets family that was found to be exclusively expressed and inducible in epithelial cells.
| ID Covalab | pab60132 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | N-terminal sequence MAATCEISNIFSNYFS and C-terminal sequence SSGWKEEEVLQSRN of human ESE-1 protein. |
| Activity cross reaction | Reacts with human ESE-1. |
| Species | Hu |
| Labelling | None |
| Form | Purified |
| Preservative | Na3 0.02% |
| Storage instructions | Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | ESE-1 |
| Uniprot ID | P78545 |
| Gene ID | 1999 |
| Applications | ELISA, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: WB (1:500 - 1:1000) ELISA (1:1000 - 1:5000) |
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