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MBD3 antibody
Methyl-CpG-binding domain protein 3
Methyl-CpG-binding protein MBD3
Gene name : MBD3
Methyl-CpG-binding protein MBD3
Gene name : MBD3
As low as
€294.00
In stock
Ref
00106921
Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides. Recruits histone deacetylases and DNA methyltransferases.
| ID Covalab | pab0980-P |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide of derived from C terminal part of human MBD3. |
| Activity cross reaction | Reacts with MBD3 from human, mouse, rat, hamster, monkeys and other species (due to sequence homology). |
| Species | Ham, Hu, Mk, Ms, Rat |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | MBD3 |
| Uniprot ID | O95983 |
| Gene ID | 53615 |
| Applications | ELISA, ICC, IF, WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: - WB : 1/500 to 1/2000 - ICC, IF: 1/200 to 1/1000 |
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