LC3B peptide

Microtubule-associated proteins 1A/1B light chain 3B
Autophagy-related protein LC3 B
Autophagy-related ubiquitin-like modifier LC3 B
MAP1 light chain 3-like protein 2
MAP1A/MAP1B light chain 3 B, MAP1A/MAP1B LC3 B
Microtubule-associated protein 1 light chain 3 beta
Gene name: MAP1LC3B, MAP1ALC3
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00102054
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
More Information
ID Covalab pep50016
Product type Peptides
Activity cross reaction Used as a blocking peptide for pab50206, pab50623, pab50624, pab50625, pab50626, pab50627. This peptide is specific for LC3B.
Species Ba, Bov, Hu, Ms, Rat, Zfi
Labelling None
Antibody / Antigen pab50206
Preservative None
Storage instructions Store at -80C. Avoid freeze-thaw cycles.
Target LC3B
Uniprot ID Q9GZQ8
Gene ID 81631
Description IHC, IHC - P, WB
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