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APP (aa737-751) antibody
Amyloid beta A4 protein
ABPP
APPI (APP)
Alzheimer disease amyloid protein
Cerebral vascular amyloid peptide (CVAP)
PreA4
Protease nexin-II (PN-II)
APP, AAA, ABETA, ABPP, AD1, Alzheimer's disease amyloid A4 protein, Amyloid beta peptide, Amyloid beta precursor protein, APPI, Beta amyloid, CTFgamma, CVAP, PN2
ABPP
APPI (APP)
Alzheimer disease amyloid protein
Cerebral vascular amyloid peptide (CVAP)
PreA4
Protease nexin-II (PN-II)
APP, AAA, ABETA, ABPP, AD1, Alzheimer's disease amyloid A4 protein, Amyloid beta peptide, Amyloid beta precursor protein, APPI, Beta amyloid, CTFgamma, CVAP, PN2
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15805
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP.
Implicated in Notch signaling pathway
Implicated in Notch signaling pathway
| ID Covalab | pab70334 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide from human APP. |
| Activity cross reaction | Reacts with peptide corresponding to amino acids 737 to 751 of human amyloid A4 protein precursor (APP) or 85 to 99 of the C99 fragment generated by b-secretase cleavage. May cross react with monkey, mouse, rat, chicken, and a variety of other species due to sequence homology. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Target | APP |
| Accession Number | P05067 |
| Applications | IHC, IHC - P, WB |
| Working dilutions | IHC (2 µg/ml), IHC - P (5 µg/ml), WB (2 µg/ml) |
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