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Vesicular Glutamate transporter type 1 antibody
Vesicular Glutamate transporter type 1 (VGluT1)
Brain-specific Na(+)-dependent inorganic phosphate cotransporter
Solute carrier family 17 member 7
Gene name : Slc17a7, Bnpi, Vglut1
Brain-specific Na(+)-dependent inorganic phosphate cotransporter
Solute carrier family 17 member 7
Gene name : Slc17a7, Bnpi, Vglut1
As low as
$323.40
In stock
Ref
00013303
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
| ID Covalab | pab0047-P |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | A 17 residue synthetic peptide derived from C-terminal domain of rat. Vesicular Glutamate Transporter Type 1 (MW : 55-60 kD) |
| Activity cross reaction | Reacts with rat 55-60 kDa VGLUT1 protein of BON cells stably expressing VGLUT1 and of total rat brain extracts. No cross reactivity was detected with VGLUT2 and VGLUT3 |
| Species | Rat |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Vesicular Glutamate transporter type 1 (VGluT1) |
| Uniprot ID | Q62634 |
| Applications | ELISA, EM, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : - EM : 1/200 - RIA : 1/500 - WB : 1/500 |
| Publication | - Kashani A, Lepicard E, Poirel O, Videau C, David JP, Fallet-Bianco C, Simon A, Delacourte A, Giros B, Epelbaum J, Betancur C, El Mestikawy S. Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease. Neurobiol Aging. 2008 Nov;29(11):1619-30. - Herzog E, Bellenchi GC, Gras C, Bernard V, Ravassard P, Bedet C, Gasnier B, Giros B, El Mestikawy S. The existence of a second vesicular glutamate transporter specifies subpopulations of glutamatergic neurons. J Neurosci. 2001 Nov 15;21(22):RC181. |
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