Charged multivesicular body protein 2b (CHMP2b) antibody

Charged multivesicular body protein 2b
CHMP2.5
Chromatin-modifying protein 2b (CHMP2b)
Vacuolar protein sorting-associated protein 2-2 (Vps2-2), (hVps2-2)
Gene name : CHMP2B
As low as $323.40
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00013498
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Belongs to the SNF7 family.
More Information
ID Covalab pab0841-P
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Human CHMP2b recombinant protein tagged with MBP.
Activity cross reaction Reacts with human CHMP2b.
Species Hu
Labelling None
Form Purified (protein A)
Preservative None
Storage instructions Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target Charged multivesicular body protein 2b (CHMP2b)
Uniprot ID Q9UQN3
Gene ID 25978
Applications ELISA, IF, WB
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB 1:200 - 1:5 000
IF 1:100 - 1:2 000
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