We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Netrin receptor UNC5B antibody
Protein unc-5 homolog 2
Protein unc-5 homolog B
p53-regulated receptor for death and life protein 1
Gene name : UNC5B, P53RDL1, UNC5H2
Protein unc-5 homolog B
p53-regulated receptor for death and life protein 1
Gene name : UNC5B, P53RDL1, UNC5H2
As low as
$323.40
In stock
Ref
00014119
Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity
| ID Covalab | pab0700-P |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | UNC5B human recombinant protein |
| Activity cross reaction | Reacts with human, mouse, rat UNC5B. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Netrin receptor UNC5B |
| Uniprot ID | Q8IZJ1 |
| Applications | ELISA, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: WB (1:500 - 1:5000) IHC (1:100 - 1:500) |
Write Your Own Review