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E3 ubiquitin-protein ligase TRIM22 antibody
50 kDa-stimulated trans-acting factor
RING finger protein 94
Staf-50
Tripartite motif-containing protein 22
Gene name: TRIM22, RNF94, STAF50
RING finger protein 94
Staf-50
Tripartite motif-containing protein 22
Gene name: TRIM22, RNF94, STAF50
As low as
$323.40
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00014373
Interferon-induced antiviral protein involved in cell innate immunity. The antiviral activity could in part be mediated by TRIM22-dependent ubiquitination of viral proteins. Plays a role in restricting the replication of HIV-1, encephalomyocarditis virus (EMCV) and hepatitis B virus (HBV). Acts as a transcriptional repressor of HBV core promoter.
| ID Covalab | pab0631-P |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide derived from an internal domain of human TRIM22 |
| Activity cross reaction | Reacts with human 57 kDa Staf-50. May cross react with proteins from other species due to sequence homology |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | E3 ubiquitin-protein ligase TRIM22 |
| Uniprot ID | Q8IYM9 |
| Applications | ELISA, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : - IHC : 1/50 to 1/500 - WB : 1/200 to 1/2 000 |
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