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MTH1 antibody
7,8-dihydro-8-oxoguanine triphosphatase
2-hydroxy-dATP diphosphatase
8-oxo-dGTPase
Nucleoside diphosphate-linked moiety X motif 1, Nudix motif 1
Gene name: NUDT1, MTH1
2-hydroxy-dATP diphosphatase
8-oxo-dGTPase
Nucleoside diphosphate-linked moiety X motif 1, Nudix motif 1
Gene name: NUDT1, MTH1
As low as
$528.40
In stock
Ref
00024774
MTH1 (human MutT Homolog 1) is an oxidized purine nucleoside triphosphatase enzyme that belongs to the Nudix hydrolase family and it acts as major mammalian detoxifier of the oxidized DNA precursor, 8-oxo-dGTP thereby exerting antimutagenic effects and suppressing cell dysfunction/death induced by oxidative stress.
| ID Covalab | pab50073 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide derived from the Cter domain of human MTH1 conjugated to KLH |
| Activity cross reaction | Reacts with human, mouse and rat MTH1. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.05% |
| Storage instructions | Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
| Target | MTH1 |
| Uniprot ID | P36639 |
| Gene ID | 4521 |
| Applications | ICC, IF, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : WB 1:500 IHC 1:200 ICC/IF 1:50-1:200 |
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