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RhoH antibody
GTP-binding protein TTF
Translocation three four protein
Gene name: RHOH, ARHH, TTF
Translocation three four protein
Gene name: RHOH, ARHH, TTF
As low as
$323.40
In stock
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00096257
Negative regulator of hematopoietic progenitor cell proliferation, survival and migration. Critical regulator of thymocyte development and T-cell antigen receptor (TCR) signaling by mediating recruitment and activation of ZAP70. Required for phosphorylation of CD3Z, membrane translocation of ZAP70 and subsequent activation of the ZAP70-mediated pathways. Essential for efficient beta-selection and positive selection by promoting the ZAP70-dependent phosphorylation of the LAT signalosome during pre-TCR and TCR signaling. Crucial for thymocyte maturation during DN3 to DN4 transition and during positive selection.
| ID Covalab | pab0942-P |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide derived from C terminal domain of human RhoH |
| Activity cross reaction | Reacts with human RhoH protein. |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Rho-related GTP-binding protein RhoH |
| Uniprot ID | Q15669 |
| Applications | ELISA, IHC, WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: - IHC : 1/200 to 1/2 000 - WB : 1/500 to 1/5 000 |
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