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Blimp-1 antibody (3H2-E8)
PR domain zinc finger protein 1
BLIMP-1
Beta-interferon gene positive regulatory domain I-binding factor
PR domain-containing protein 1
Positive regulatory domain I-binding factor 1 (PRDI-BF1), (PRDI-binding factor 1)
Gene name: PRDM1, BLIMP1
BLIMP-1
Beta-interferon gene positive regulatory domain I-binding factor
PR domain-containing protein 1
Positive regulatory domain I-binding factor 1 (PRDI-BF1), (PRDI-binding factor 1)
Gene name: PRDM1, BLIMP1
As low as
$528.40
In stock
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00098920
Blimp-1 (B lymphocyte maturation protein-1) is a nuclear protein with five zinc fingers in its carboxy terminus.It is a transcriptional repressor that is both required and sufficient to trigger terminal differentiation of B lymphocytes and monocyte/macrophages.Blimp-1 is expressed in, and may be required for terminally differentiated epithelial cells, retinal neurons and other lineage cells.Blimp-1 has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression.
| ID Covalab | mab50071 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 3H2-E8 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | A fragment of the mouse Blimp-1 (residues 199-409) |
| Activity cross reaction | Reacts with ~98 kDa BLIMP-1 from mouse, pig and human. May cross reacts with the beta form (~80 kDa). |
| Species | Hu, Ms, Po |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | NaN3 0.1% |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | B lymphocyte-induced maturation protein-1 (BLIMP-1) |
| Uniprot ID | O75626 |
| Gene ID | 639 |
| Applications | ELISA, FC, ICC, IF, IHC, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : - ELISA: 1/100 to 1/2000 - ICC/ IF: 1/50 to 1/100 - IHC: 1/200 -FC: 8 µg/ml (for 2 x 10E6 cells/ml) - WB: 1/1000 |
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