Prohibitin-2 antibody

B-cell receptor-associated protein BAP37
D-prohibitin
Repressor of estrogen receptor activity
Gene name : PHB2, BAP, REA
BCAP37, Bap37, PNAS-141, p22
As low as $323.40
In stock
Ref
00106927
Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
More Information
ID Covalab pab0981-P
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide of derived from C terminal part of human Prohibitin-2.
Activity cross reaction Reacts with MBD3 from human, mouse, rat and other species (due to sequence homology).
Species Hu, Ms, Rat
Labelling None
Form Purified (protein A)
Preservative None
Storage instructions Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target Prohibitin-2
Uniprot ID Q99623
Gene ID 11331
Applications ELISA, ICC, IF, WB
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000
- ICC, IF: 1/200 to 1/1000
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