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HDAC6 antibody (159)
Histone deacetylase 6 (HD6)
Tubulin-lysine deacetylase HDAC6
Gene name: HDAC6
Tubulin-lysine deacetylase HDAC6
Gene name: HDAC6
As low as
$448.50
In stock
Ref
00118920
Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.
| ID Covalab | mab21311 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 159 |
| Isotype | IgG1 kappa |
| Raised in | Mouse |
| Immunogen | The mouse monoclonal antibody 159 recognizes SE domain of human histone deacetylase 6 (HDAC6; an intracellular antigen), amino acids 971-981. Crossreactivity with other species was not tested. |
| Activity cross reaction | Human HDAC6 |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | NaN3 15 mM |
| Storage instructions | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. |
| Target | HDAC6 |
| Uniprot ID | Q9UBN7 |
| Gene ID | 10013 |
| Applications | ELISA, FC, ICC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. |
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