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MOG peptide (35-55)
Myelin Oligodendrocyte Glycoprotein Peptide Fragment 35-55
Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys
Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys
As low as
$247.75
In stock
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00110288
The MOG peptide (35-55) has been described to induce autoimmune encephalomyelitis associated with Parkinson disease. It induces extensive plaque-like demyelination after a single injection. Immunization with this peptide blocks the regeneration of dopaminergic neurons injured with MPTP.
| ID Covalab | pep90001 |
|---|---|
| Product type | Peptides |
| Target domain | 33 - 55 |
| Activity cross reaction | Mouse Gene ID: 17441 Uniprot ID: Q61885 Rat Gene ID: 24558 Uniprot ID: Q63345 |
| Species | Ms, Rat |
| Labelling | None |
| Antibody / Antigen | pab72397 |
| Sequence | MEVGWYRSPFSRVVHLYRNGK |
| Modifications | None |
| Pureté | >98% |
| Preservative | None |
| Storage instructions | Store at −20°C |
| Target | MOG (35-55) |
| CAS Number | 163913-87-9 |
| Publication | * Marrocco R et al. Positive regulation of Vav1 by Themis controls CD4 T cell pathogenicity in a mouse model of central nervous system inflammation. Cell. Mol. Life Sci. 81, 161 (2024). *Yshii et al.Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation NATURE IMMUNOLOGY. 2022 Juin. |
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