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CD106 antibody (429 (MVCAM.A)) [FITC]
Vascular cell adhesion protein 1
Gene name: Vcam1
Gene name: Vcam1
As low as
$311.50
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00118342
CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity.
| ID Covalab | mab21284 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 429 (MVCAM.A) |
| Isotype | IgG2a kappa |
| Raised in | Rat |
| Immunogen | The rat monoclonal antibody 429 (also known as MVCAM.A) recognizes murine CD106, a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule. |
| Activity cross reaction | Murine preadipose cell line PA6. |
| Species | Ms |
| Labelling | FITC |
| Form | Purified |
| Preservative | NaN3 15 mM |
| Storage instructions | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label. |
| Target | CD106 |
| Uniprot ID | Q3UPN1 |
| Gene ID | 22329 |
| Applications | FC |
| Working dilutions | Optimal dilutions should be determined by the end user. |
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