We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
CD26 antibody (H194-112)
Dipeptidyl peptidase 4 (DPP 4, DPP IV)
T-cell activation antigen CD26
Thymocyte-activating molecule (THAM)
Gene name: Dpp4, Cd26
T-cell activation antigen CD26
Thymocyte-activating molecule (THAM)
Gene name: Dpp4, Cd26
As low as
$326.10
In stock
Ref
00118344
CD26, also known as dipeptidyl peptidase IV (DPP-IV), is a homodimeric cell surface serine peptidase that degradates IFN-gamma-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumour grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.
| ID Covalab | mab21285 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | H194-112 |
| Isotype | IgG2a kappa |
| Raised in | Rat |
| Immunogen | The rat monoclonal antibody H194-112 recognizes CD26, a 110 kDa type II membrane glycoprotein, which is a peptidase expressed on mature thymocytes, T cells (especially activated), B cells, NK cells and macrophages. |
| Activity cross reaction | BALB/c thymocytes |
| Species | Ms |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | NaN3 15 mM |
| Storage instructions | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. |
| Target | CD26 |
| Uniprot ID | P28843 |
| Gene ID | 13482 |
| Applications | FC, IHC-F, IP |
| Working dilutions | Optimal dilution should be determined by the end user. |
Write Your Own Review