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ATG7 (aa558-569) antibody
Ubiquitin-like modifier-activating enzyme ATG7
ATG12-activating enzyme E1 ATG7
Autophagy-related protein 7 (APG7-like) (hAGP7)
Ubiquitin-activating enzyme E1-like protein
APG7-LIKE, DKFZp434N0735, GSA7
Gene name: ATG7, APG7L
ATG12-activating enzyme E1 ATG7
Autophagy-related protein 7 (APG7-like) (hAGP7)
Ubiquitin-activating enzyme E1-like protein
APG7-LIKE, DKFZp434N0735, GSA7
Gene name: ATG7, APG7L
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00015094
Functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. Forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). PE-conjugation to ATG8-like proteins is essential for autophagy. Also acts as an E1 enzyme for ATG12 conjugation to ATG5 and ATG3
ID Covalab | pab70082 |
---|---|
Product type | Primary antibodies |
Clonality | Polyclonal antibody |
Raised in | Rabbit |
Immunogen | Synthetic peptide from human ATG7 (aa 558 to 569). |
Activity cross reaction | Reacts with Human Apg7 protein. |
Species | Hu |
Labelling | None |
Form | Antigen affinity purified |
Preservative | NaN3 0.01% |
Storage instructions | +4°C or -20°C, Avoid repeated freezing and thawing. |
Target | ATG7 |
Uniprot ID | O95352 |
Gene ID | 10533 |
Applications | ELISA, IF, IHC - P, WB |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : ELISA (1/15000 - 1/75000), IHC - P (10 µg/ml), WB (1/500 - 1/2000) |
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