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AXIN1 (C-Terminus) antibody
Axin-1
Axis inhibition protein 1 (hAxin)
AXIN1, AXIN, MGC52315
Axis inhibition protein 1 (hAxin)
AXIN1, AXIN, MGC52315
As low as
$608.60
In stock
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00015848
Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects; down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.
| ID Covalab | pab70377 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | 14 amino acid peptide near the carboxy terminus of human AXIN1 |
| Activity cross reaction | Reacts with human AXIN1. |
| Species | Hu |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Target | AXIN1 |
| Accession Number | O15169 |
| Applications | IHC - P, WB |
| Working dilutions | IHC - P (5 µg/ml), WB (1 - 2 µg/ml) |
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