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BACE2 (aa44-59) antibody
Beta-secretase 2
Aspartic-like protease 56 kDa
Aspartyl protease 1 (ASP1) (Asp 1)
Beta-site amyloid precursor protein cleaving enzyme 2 (Beta-site APP cleaving enzyme 2)
Down region aspartic protease (DRAP)
Memapsin-1
Membrane-associated aspartic protease 1
Theta-secretase
BACE2, AEPLC, ALP56, APL56, ASP21, BAE2, Beta-site amyloid beta A4 precursor protein-cleaving enzyme 2, CDA13, CEAP1
Aspartic-like protease 56 kDa
Aspartyl protease 1 (ASP1) (Asp 1)
Beta-site amyloid precursor protein cleaving enzyme 2 (Beta-site APP cleaving enzyme 2)
Down region aspartic protease (DRAP)
Memapsin-1
Membrane-associated aspartic protease 1
Theta-secretase
BACE2, AEPLC, ALP56, APL56, ASP21, BAE2, Beta-site amyloid beta A4 precursor protein-cleaving enzyme 2, CDA13, CEAP1
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00015854
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
| ID Covalab | pab70383 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide from human BACE2. |
| Activity cross reaction | Reacts with synthetic peptide (aptpgpgtpaerhadg) corresponding to amino acids 44 to 59 of human BACE2 |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Target | BACE2 |
| Accession Number | Q9Y5Z0 |
| Applications | ELISA, IHC - P, WB |
| Working dilutions | ELISA, IHC - P (5 µg/ml), WB (0.5 - 1 µg/ml) |
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