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p53 antibody (B-F34)
Cellular tumor antigen p53
Antigen NY-CO-13
Phosphoprotein p53
Tumor suppressor p53
Gene name: TP53, P53
Antigen NY-CO-13
Phosphoprotein p53
Tumor suppressor p53
Gene name: TP53, P53
As low as
$311.50
In stock
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00036985
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
| ID Covalab | mab30071 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | B-F34 |
| Isotype | IgG2b / Kappa |
| Raised in | Mouse |
| Immunogen | Recombinant p53 protein |
| Activity cross reaction | Reacts with wild type and mutant p53, the epitope is within residues 18-30 of human p53 |
| Species | Hu |
| Labelling | None |
| Form | Purified |
| Preservative | None |
| Storage instructions | Stable at +2-8°C for 12 months For longer storage, freeze aliquots Antibodies are guaranteed for 6 months from date of receipt. |
| Target | p53 |
| Uniprot ID | P04637 |
| Gene ID | 7157 |
| Applications | ELISA |
| Working dilutions | Optimal dilutions should be determined by the end user. |
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