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Delta GABA-A Receptor (S151-3) antibody
gamma-aminobutyric acid (GABA) A receptor, subunit delta
As low as
$669.90
In stock
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00096620
GABA is the major inhibitory neurotransmitter in the vertebrate brain. GABA receptors consist of five subunits that form a chloride ion channel. Subunit families α, β, γ, and δ have been studied extensively, π and ε have been identified recently.
Studies of recombinant GABA receptors have shown that individual subunits and their subtypes confer different sensitivities
to GABA receptor modulators. Subunit subtypes are differentially expressed throughout development and in different CNS regions, reducing the total number of possible isoforms that can be formed in different brain regions and in individual cells.
Studies of recombinant GABA receptors have shown that individual subunits and their subtypes confer different sensitivities
to GABA receptor modulators. Subunit subtypes are differentially expressed throughout development and in different CNS regions, reducing the total number of possible isoforms that can be formed in different brain regions and in individual cells.
| ID Covalab | mab60107 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | S151-3 |
| Isotype | IgG2a |
| Raised in | Mouse |
| Immunogen | Synthetic peptide corresponding to aa 15-34 of rat Delta GABA-A receptor (accession no. P18506). |
| Activity cross reaction | Reacts with mouse Delta GABA-A Receptor. Cross-reacts with rat protein. |
| Species | Ms, Rat |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | 0,09% NaN3 |
| Storage instructions | Store at -20°C, stable for one year. Avoid repeated freeze thaw cycles. |
| Target | Delta GABA-A Receptor |
| Uniprot ID | P22933 |
| Gene ID | 14403 |
| Applications | ICC, IF, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : ICC (0.1 - 1 µg/ml) IHC (0.1 - 1 µg/ml) IF (1 - 10 µg/ml) WB (1 - 10 µg/ml) A band of ~55kDa is detected |
| Positive control | Rat brain |
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