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Dicer (S167-7) antibody
Helicase with RNase motif
Helicase MOI
Gene name : DICER1
Helicase MOI
Gene name : DICER1
As low as
$669.90
In stock
Ref
00096621
Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs). After long primary transcript pri-miRNAs are processed to stem-looped premiRNAs by Drosha, pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs . The mature miRNA then becomes a part of the RNA Induced Silencing Complex (RISC) and can bind to the 3' UTR of the target mRNA.
| ID Covalab | mab60108 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | S167-7 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Fusion protein corresponding to aa 1638-1899 of mouse Endoribonuclease Dicer (accession no.Q8R418). |
| Activity cross reaction | Reacts with human Dicer. Cross-reacts with rat protein. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | 0.09% NaN3 |
| Storage instructions | This antibody is stable for at least one year at -20°C. Avoid repeated freeze-thaw cycles. |
| Target | Dicer |
| Uniprot ID | Q9UPY3 |
| Gene ID | 23405 |
| Applications | ICC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : WB (1 µg/ml). |
| Positive control | Rat brain lysate. |
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