E-Cadherin (SHE78-7) antibody

Cadherin-1
CAM 120/80
Epithelial cadherin, E-cadherin
Uvomorulin
CD324
Gene name: CDH1, CDHE, UVO, Arc-1, CDHE, ECAD, LCAM
As low as $689.70
In stock
Ref
00096634
This antibody inhibits E-Cadherin dependent cell-cell contact.
More Information
ID Covalab mab60121
Product type Primary antibodies
Clonality Monoclonal antibody
Clone SHE78-7
Isotype IgG2a
Raised in Mouse
Immunogen Human placenta E-Cadherin
Activity cross reaction Reacts with human E-Cadherin. No cross-reaction with rat E-Cadherin.
Species Hu
Labelling None
Form Purified
Preservative None
Storage instructions Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 months from date of receipt.
Target E-Cadherin
Uniprot ID P12830
Gene ID 999
Applications ELISA, FA, FC, IF, IHC, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ELISA (2 µg/ml)
WB (2 µg/ml, reducing and non-reducing conditions)
IHC (2 µg/ml, paraffin or frozen)
IF (1 µg/ml)
FC (1 µg/ml)
Cell-Cell Contact Inhibition Assays (1 µg/ml)
Publication * Watabe M et al. Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line. J Cell Biol. 1994 Oct,127(1):247-56.
* Katayama M et al. Soluble E-cadherin fragments increased in circulation of cancer patients. Br J Cancer.
1994 Mar,69(3):580-5.
* Katayama M et al. Soluble fragments of e-cadherin cell-adhesion molecule increase in urinary-excretion of cancer-patients, potentially indicating its shedding from epithelial tumor-cells. Int J Oncol. 1994 Nov,5(5):1049-57.
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