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CIDE-3 antibody
Cell death activator CIDE-3
Cell death-inducing DFFA-like effector protein C
Fat-specific protein FSP27
Gene name: Cidec, Fsp27
Cell death-inducing DFFA-like effector protein C
Fat-specific protein FSP27
Gene name: Cidec, Fsp27
As low as
$579.70
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00097784
DNA fragmentation, induced by DNA fragmentation factor (DFF), is one of the critical steps in apoptosis. DFF is composed of two subunits, a 40-kDa caspase-activated nuclease (DFF40) and a 45-kDa inhibitor (DFF45). Recently a novel family of cell death-inducing DFF45-like effectors (CIDEs) has been identified. Human CIDE-3 is a novel CIDE. Two transcripts, CIDE-3 and CIDE-3alpha, are present in HepG2 and A375 cells. Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumors, CIDE-3 may play an important role in prevention of tumorigenesis.
| ID Covalab | pab60078 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide corresponding to amino acids 10-25 (LLYPKSLSRHVSVRTS) of human CIDE-3 conjugated to KLH at the C-terminus. |
| Activity cross reaction | Reacts with human CIDE-3. Sequence homology to the mouse CIDE-3 homolog, FSP27, is 93%. |
| Species | Hu |
| Labelling | None |
| Form | Purified |
| Preservative | None |
| Storage instructions | Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | CIDE-3 |
| Uniprot ID | P56198 |
| Gene ID | 14311 |
| Applications | ELISA, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: WB (1:5000) |
| Publication | * Liang L et al. Biochem J. 2003 Feb 15,370(Pt 1):195-203. |
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