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Hippo Pathway
Hippo-related products from Covalab
Cytoskeleton
This branch is defined by an as yet poorly understood signalling mechanism mediated by the cytoskeleton. GPCRs relay signal from soluble extracellular cues and cell matrix attachment to activate RHO GTPases. This induces a modification of the actin cytoskeleton that inhibits YAP/TAZ complex nuclear translocation, thus negatively regulating the Hippo cascade.
Anti-GPR12 antibody IHC staining of formalin-fixed, paraffin-embedded human pituitary gland after heat-induced antigen retrieval.
Anti-GPR12 antibody IHC staining of formalin-fixed, paraffin-embedded human pituitary gland after heat-induced antigen retrieval.
Anti-GPR12 antibody IHC staining of formalin-fixed, paraffin-embedded human anterior pituitary gland after heat-induced antigen retrieval.
Anti-GPR12 antibody IHC staining of formalin-fixed, paraffin-embedded human pituitary gland after heat-induced antigen retrieval.
Anti-GPR18 antibody IHC staining of formalin-fixed, paraffin-embedded human spleen after heat-induced antigen retrieval.
FC count of fixed and permeabilized Y79 cells stained with anti-Rhodopsin antibody (red).
Anti-Rhodopsin antibody IHC staining of formalin-fixed, paraffin-embedded human retina after heat-induced antigen retrieval.